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Romero-Torrecilla J.A., Lamo-Espinosa J.M., Ripalda-Cemboráin P., López-Martínez T., Abizanda G., Riera-Álvarez L., de Galarreta-Moriones S.R., López-Barberena A., Rodríguez-Flórez N., Elizalde R., Jayawarna V., Valdés-Fernández J., de Anleo M.E.G., Childs P., de Juan-Pardo E., Salmeron-Sanchez M., Prósper F., Muiños-López E., Granero-Moltó F.. An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration. npj Regenerative Medicine. December 2023. DOI: 10.1038/s41536-023-00330-2.

Aparicio B., Lasarte J.J., Sarobe P.. Mutated trimeric RBD vaccines: a platform against variants of concern. Signal Transduction and Targeted Therapy. December 2023. DOI: 10.1038/s41392-023-01426-3.

Perez-Estenaga I., Chevalier M.T., Peña E., Abizanda G., Alsharabasy A.M., Larequi E., Cilla M., Perez M.M., Gurtubay J., Garcia-Yebenes Castro M., Prosper F., Pandit A., Pelacho B.. A Multimodal Scaffold for SDF1 Delivery Improves Cardiac Function in a Rat Subacute Myocardial Infarct Model. ACS Applied Materials and Interfaces. 8 November 2023. DOI: 10.1021/acsami.3c04245.

Pitchaimani A., Ferreira M., Palange A., Pannuzzo M., De Mei C., Spano R., Marotta R., Pelacho B., Prosper F., Decuzzi P.. Compartmentalized drug localization studies in extracellular vesicles for anticancer therapy. Nanoscale Advances. 8 November 2023. DOI: 10.1039/d3na00207a.

Cortés A., Marqués J., Pejenaute Á., Ainzúa E., Ansorena E., Abizanda G., Prósper F., de Miguel C., Zalba G.. Endothelial NOX5 overexpression induces changes in the cardiac gene profile: potential impact in myocardial infarction?. Journal of Physiology and Biochemistry. November 2023. DOI: 10.1007/s13105-023-00975-z.

Shiroud Heidari B., Lopez E.M., Chen P., Ruan R., Vahabli E., Davachi S.M., Granero-Moltó F., De-Juan-Pardo E.M., Zheng M., Doyle B.. Silane-modified hydroxyapatite nanoparticles incorporated into polydioxanone/poly(lactide-co-caprolactone) creates a novel toughened nanocomposite with improved material properties and in vivo inflammatory responses. Materials Today Bio. October 2023. DOI: 10.1016/j.mtbio.2023.100778.

Lasaga M., Río P., Vilas-Zornoza A., Planell N., Navarro S., Alignani D., Fernández-Varas B., Mouzo D., Zubicaray J., Pujol R.M., Nicoletti E., Schwartz J.D., Sevilla J., Ainciburi M., Ullate- Agote A., Surrallés J., Perona R., Sastre L., Prosper F., Gomez-Cabrero D., Bueren J.A.. Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia. Haematologica. October 2023. DOI: 10.3324/haematol.2022.282418.

Clavería-Cabello A., Herranz J.M., Latasa M.U., Arechederra M., Uriarte I., Pineda-Lucena A., Prosper F., Berraondo P., Alonso C., Sangro B., García Marin J.J., Martinez-Chantar M.L., Ciordia S., Corrales F.J., Francalanci P., Alaggio R., Zucman-Rossi J., Indersie E., Cairo S., Domingo-Sàbat M., Zanatto L., Sancho-Bru P., Armengol C., Berasain C., Fernandez-Barrena M.G., Avila M.A.. Identification and experimental validation of druggable epigenetic targets in hepatoblastoma. Journal of Hepatology. October 2023. DOI: 10.1016/j.jhep.2023.05.031.

Lara-Astiaso D., Goñi-Salaverri A., Mendieta-Esteban J., Narayan N., Del Valle C., Gross T., Giotopoulos G., Beinortas T., Navarro-Alonso M., Aguado-Alvaro L.P., Zazpe J., Marchese F., Torrea N., Calvo I.A., Lopez C.K., Alignani D., Lopez A., Saez B., Taylor-King J.P., Prosper F., Fortelny N., Huntly B.J.P.. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis. Nature Genetics. September 2023. DOI: 10.1038/s41588-023-01471-2.

El Moukhtari S.H., Garbayo E., Amundarain A., Pascual-Gil S., Carrasco-León A., Prosper F., Agirre X., Blanco-Prieto M.J.. Lipid nanoparticles for siRNA delivery in cancer treatment. Journal of Controlled Release. September 2023. DOI: 10.1016/j.jconrel.2023.07.054.

Costa M.H.G., Costa M.S., Painho B., Sousa C.D., Carrondo I., Oltra E., Pelacho B., Prosper F., Isidro I.A., Alves P., Serra M.. Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell-derived extracellular vesicles in stirred-tank bioreactors. Biotechnology and Bioengineering. September 2023. DOI: 10.1002/bit.28378.

Martinez-De-morentin X., Khan S.A., Lehmann R., Qu S., Maillo A., Kiani N.A., Prosper F., Tegner J., Gomez-Cabrero D.. LIBRA: an adaptative integrative tool for paired single-cell multi-omics data. Quantitative Biology. September 2023. DOI: 10.15302/J-QB-022-0318.

Nicola Candia A.J., Garcia Fallit M., Peña Agudelo J.A., Pérez Küper M., Gonzalez N., Moreno Ayala M.A., De Simone E., Giampaoli C., Casares N., Seilicovich A., Lasarte J.J., Zanetti F.A., Candolfi M.. Targeting FOXP3 Tumor-Intrinsic Effects Using Adenoviral Vectors in Experimental Breast Cancer. Viruses. September 2023. DOI: 10.3390/v15091813.

Aguilar S., García-Olloqui P., Amigo-Morán L., Torán J.L., López J.A., Albericio G., Abizanda G., Herrero D., Vales Á., Rodríguez-Diaz S., Higuera M., García-Martín R., Vázquez J., Mora C., González-Aseguinolaza G., Prosper F., Pelacho B., Bernad A.. Cardiac Progenitor Cell Exosomal miR-935 Protects against Oxidative Stress. Cells. September 2023. DOI: 10.3390/cells12182300.

Marin-Bejar O., Romero-Moya D., Rodriguez-Ubreva J., Distefano M., Lessi F., Aretini P., Liquori A., Castaño J., Kozyra E., Kotmayer L., Bueno C., Cervera J., Rodriguez-Gallego J.C., Nomdedeu J.F., Murillo- Sanjuán L., de Heredia C.D., Pérez-Martinez A., López-Cadenas F., Martínez-Laperche C., Dorado-Herrero N., Marco F.M., Prósper F., Menendez P., Valcárcel D., Ballestar E., Bödör C., Bigas A., Catalá A., Wlodarski M.W., Giorgetti A.. Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency. Haematologica. September 2023. DOI: 10.3324/haematol.2022.282305.

Montero-Calle P., Flandes-Iparraguirre M., Kuebler B., Arán B., Larequi E., Anaut I., Coppiello G., Aranguren X.L., Veiga A., Elorz M.T.B., de Yébenes M.G., Gavira J.J., Prósper F., Iglesias-García O., Vega M.M.M.. Generation of an induced pluripotent stem cell line (ESi107-A) from a transthyretin amyloid cardiomyopathy (ATTR-CM) patient carrying a p.Ser43Asn mutation in the TTR gene. Stem Cell Research. September 2023. DOI: 10.1016/j.scr.2023.103189.

Bocanegra A., Fernández-Hinojal G., Ajona D., Blanco E., Zuazo M., Garnica M., Chocarro L., Alfaro-Arnedo E., Piñeiro-Hermida S., Morente P., Fernández L., Remirez A., Echaide M., Martinez-Aguillo M., Morilla I., Tavira B., Roncero A., Gotera C., Ventura A., Recalde N., Pichel J.G., Lasarte J.J., Montuenga L., Vera R., Pio R., Escors D., Kochan G.. Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer. EMBO Reports. 3 August 2023. DOI: 10.15252/embr.202255884.

Oliver-Caldés A., González-Calle V., Cabañas V., Español-Rego M., Rodríguez-Otero P., Reguera J.L., López-Corral L., Martin-Antonio B., Zabaleta A., Inogés S., Varea S., Rosiñol L., López-Díaz de Cerio A., Tovar N., Jiménez R., López-Parra M., Rodríguez-Lobato L.G., Sánchez-Salinas A., Olesti E., Calvo-Orteu M., Delgado J., Pérez-Simón J.A., Paiva B., Prósper F., Sáez-Peñataro J., Juan M., Moraleda J.M., Mateos M.V., Pascal M., Urbano-Ispizua A., Fernández de Larrea C.. Fractionated initial infusion and booster dose of ARI0002h, a humanised, BCMA-directed CAR T-cell therapy, for patients with relapsed or refractory multiple myeloma (CARTBCMA-HCB-01): a single-arm, multicentre, academic pilot study. The Lancet Oncology. August 2023. DOI: 10.1016/S1470-2045(23)00222-X.

Exposito F., Redrado M., Houry M., Hastings K., Molero-Abraham M., Lozano T., Solorzano J.L., Sanz-Ortega J., Adradas V., Amat R., Redin E., Leon S., Legarra N., Garcia J., Serrano D., Valencia K., Robles-Oteiza C., Foggetti G., Otegui N., Felip E., Lasarte J.J., Paz-Ares L., Zugazagoitia J., Politi K., Montuenga L., Calvo A.. PTEN Loss Confers Resistance to Anti–PD-1 Therapy in Non–Small Cell Lung Cancer by Increasing Tumor Infiltration of Regulatory T Cells. Cancer Research. 1 August 2023. DOI: 10.1158/0008-5472.CAN-22-3023.

Shiroud Heidari B., Muiños Lopez E., Harrington E., Ruan R., Chen P., Davachi S.M., Allardyce B., Rajkhowa R., Dilley R., Granero-Moltó F., De-Juan-Pardo E.M., Zheng M., Doyle B.. Novel hybrid biocomposites for tendon grafts: The addition of silk to polydioxanone and poly(lactide-co-caprolactone) enhances material properties, in vitro and in vivo biocompatibility. Bioactive Materials. July 2023. DOI: 10.1016/j.bioactmat.2023.02.003.

Ihejirika-Lomedico R., Patel K., Buchalter D.B., Kirby D.J., Mehta D., Dankert J.F., Muiños-López E., Ihejirika Y., Leucht P.. Non-psychoactive Cannabidiol Prevents Osteoporosis in an Animal Model and Increases Cell Viability, Proliferation, and Osteogenic Gene Expression in Human Skeletal Stem and Progenitor Cells. Calcified Tissue International. June 2023. DOI: 10.1007/s00223-023-01083-2.

Willcockson H., Ozkan H., Valdés-Fernández J., Arbeeva L., Mucahit E., Musawwir L., Hooper L.B., Granero-Moltó F., Prósper F., Longobardi L.. CC-Chemokine Receptor-2 Expression in Osteoblasts Contributes to Cartilage and Bone Damage during Post-Traumatic Osteoarthritis. Biomolecules. June 2023. DOI: 10.3390/biom13060891.

Grilli F., Albanesi E., Pelacho B., Prosper F., Decuzzi P., Di Mascolo D.. Microstructured Polymeric Fabrics Modulating the Paracrine Activity of Adipose-Derived Stem Cells. International Journal of Molecular Sciences. June 2023. DOI: 10.3390/ijms241210123.

Simoes C., Villar S., Ariceta B., Garcés J.J., Burgos L., Alignani D., Sarvide S., Martínez-Cuadrón D., Bergua J.M., Vives S., Algarra L., Tormo M., Martinez P., Serrano J., Herrera P., Ramos F., Salamero O., Lavilla E., Gil C., Lopez-Lorenzo J.L., Vidriales M.B., Chillon C., Labrador J., Falantes J.F., Sayas M.J., Ayala R., Martinez-Lopez J., Pierola A.A., Calasanz M.J., Prosper F., San-Miguel J.F., Sanz M., Paiva B., Montesinos P.. Transcriptional and genomic characterization of measurable residual disease in acute myeloid leukaemia. British Journal of Haematology. June 2023. DOI: 10.1111/bjh.18815.

Sánchez-Guijo F., Avendaño-Solá C., Badimón L., Bueren J.A., Canals J.M., Delgadillo J., Delgado J., Eguizábal C., Fernández-Santos M.E., García-Olmo D., González-Aseguinolaza G., Juan M., Martín F., Mata R., Montserrat N., Pérez-Martínez A., Pérez-Simón J.A., Prósper F., Urbano-Ispizua Á., Zapata A.G., Sureda A., Moraleda J.M.. Role of Hospital Exemption in Europe: position paper from the Spanish Advanced Therapy Network (TERAV). Bone Marrow Transplantation. June 2023. DOI: 10.1038/s41409-023-01962-0.

Perucho L., Icardi L., Di Simone E., Basso V., Agresti A., Vilas Zornoza A., Lozano T., Prosper F., Lasarte J.J., Mondino A.. The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells. EMBO Reports. 4 May 2023. DOI: 10.15252/embr.202255326.

Silva-Pilipich N., Blanco E., Lozano T., Martisova E., Igea A., Herrador-Cañete G., Ballesteros-Briones M.C., Gorraiz M., Sarrión P., González-Sapienza G., Lasarte J.J., Vanrell L., Smerdou C.. Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses. Cancer Letters. 1 May 2023. DOI: 10.1016/j.canlet.2023.216139.

Larrayoz M., Garcia-Barchino M.J., Celay J., Etxebeste A., Jimenez M., Perez C., Ordoñez R., Cobaleda C., Botta C., Fresquet V., Roa S., Goicoechea I., Maia C., Lasaga M., Chesi M., Bergsagel P.L., Larrayoz M.J., Calasanz M.J., Campos-Sanchez E., Martinez-Cano J., Panizo C., Rodriguez-Otero P., Vicent S., Roncador G., Gonzalez P., Takahashi S., Katz S.G., Walensky L.D., Ruppert S.M., Lasater E.A., Amann M., Lozano T., Llopiz D., Sarobe P., Lasarte J.J., Planell N., Gomez-Cabrero D., Kudryashova O., Kurilovich A., Revuelta M.V., Cerchietti L., Agirre X., San Miguel J., Paiva B., Prosper F., Martinez-Climent J.A.. Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma. Nature Medicine. March 2023. DOI: 10.1038/s41591-022-02178-3.

Wu M., Pelacho B., Claus P., De Buck S., Veltman D., Gillijns H., Holemans P., Pokreisz P., Caluwé E., Iglesias Colino E., Cohen S., Prosper F., Janssens S.. Alginate sulfate-nanoparticles loaded with hepatocyte growth factor and insulin-like growth factor-1 improve left ventricular repair in a porcine model of myocardial ischemia reperfusion injury. European Journal of Pharmaceutics and Biopharmaceutics. March 2023. DOI: 10.1016/j.ejpb.2023.01.012.

Mejías Sosa L., López-Janeiro Á., Córdoba Iturriagagoitia A., Sala P., Solans B.P., Hato L., Inogés S., López-Díaz de Cerio A., Guillén-Grima F., Espinós J., De La Cruz S., Lozano M.D., Idoate M.A., Santisteban M.. Modification of Breast Cancer Milieu with Chemotherapy plus Dendritic Cell Vaccine: An Approach to Select Best Therapeutic Strategies. Biomedicines. February 2023. DOI: 10.3390/biomedicines11020238.

Mateos M.V., Prosper F., Martin Sánchez J., Ocio E.M., Oriol A., Motlló C., Michot J.M., Jarque I., Iglesias R., Solé M., Martínez S., Kahatt C., Fudio S., Corral G., Zeaiter A., Montilla L., Ribrag V.. Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma. Cancer Medicine. February 2023. DOI: 10.1002/cam4.5250.

Ozkan H., Di Francesco M., Willcockson H., Valdés-Fernández J., Di Francesco V., Granero-Moltó F., Prósper F., Decuzzi P., Longobardi L.. Sustained inhibition of CC-chemokine receptor-2 via intraarticular deposition of polymeric microplates in post-traumatic osteoarthritis. Drug Delivery and Translational Research. February 2023. DOI: 10.1007/s13346-022-01235-1.

Stölzel F., Fordham S.E., Nandana D., Lin W.Y., Blair H., Elstob C., Bell H.L., Mohr B., Ruhnke L., Kunadt D., Dill C., Allsop D., Piddock R., Soura E.N., Park C., Fadly M., Rahman T., Alharbi A., Wobus M., Altmann H., Röllig C., Wagenführ L., Jones G.L., Menne T., Jackson G.H., Marr H.J., Fitzgibbon J., Onel K., Meggendorfer M., Robinson A., Bziuk Z., Bowes E., Heidenreich O., Haferlach T., Villar S., Ariceta B., Diaz R.A., Altschuler S.J., Wu L.F., Prosper F., Montesinos P., Martinez-Lopez J., Bornhäuser M., Allan J.M.. Biallelic TET2 mutations confer sensitivity to 5′-azacitidine in acute myeloid leukemia. JCI Insight. 24 January 2023. DOI: 10.1172/jci.insight.150368.

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Ainciburu M., Ezponda T., Berastegui N., Alfonso-Pierola A., Vilas-Zornoza A., San Martin-Uriz P., Alignani D., Lamo-Espinosa J., San-Julian M., Jiménez-Solas T., Lopez F., Muntion S., Sanchez-Guijo F., Molero A., Montoro J., Serrano G., Diaz-Mazkiaran A., Lasaga M., Gomez-Cabrero D., Diez-Campelo M., Valcarcel D., Hernaez M., Romero J.P., Prosper F.. Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution. eLife. 11 January 2023. DOI: 10.7554/eLife.79363.

Moya-Jódar M., Ullate-Agote A., Barlabé P., Rodríguez-Madoz J.R., Abizanda G., Barreda C., Carvajal-Vergara X., Vilas-Zornoza A., Romero J.P., Garate L., Agirre X., Coppiello G., Prósper F., Aranguren X.L.. Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures. Stem Cell Reports. 10 January 2023. DOI: 10.1016/j.stemcr.2022.11.015.

Simoes C., Chillon M.C., Martínez-Cuadrón D., Calasanz M.J., Vridiales M.B., Vazquez I., Hernández-Ruano M., Ariceta B., Aguirre-Ruiz P., Burgos L., Alignani D., Sarvide S., Villar S., Pierola A.A., Prosper F., Ayala R., Martínez-López J., Bergua Burgues J.M., Vives S., Perez-Simon J.A., Garcia-Fortes M., del Castillo T.B., Colorado M., Olave M., Rodríguez-Gutiérrez J.I., Labrador J., González M., San-Miguel J.F., Sanz M.Á., Montesinos P., Paiva B.. Integrated flow cytometry and sequencing to reconstruct evolutionary patterns from dysplasia to acute myeloid leukemia. Blood Advances. 10 January 2023. DOI: 10.1182/bloodadvances.2022008141.

Conde E., Casares N., Mancheño U., Elizalde E., Vercher E., Capozzi R., Santamaria E., Rodriguez-Madoz J.R., Prosper F., Lasarte J.J., Lozano T., Hervas-Stubbs S.. FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma. Molecular Therapy. 4 January 2023. DOI: 10.1016/j.ymthe.2022.08.017.

Aparicio B., Ruiz M., Casares N., Silva L., Egea J., Pérez P., Albericio G., Esteban M., García-Arriaza J., Lasarte J.J., Sarobe P.. Erratum: Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodies(Front. Immunol., (2023), 13, (1044025), 10.3389/fimmu.2022.1044025). Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1172427.

Ceballos C., Viguria M.C., Panizo C., Rodríguez-Madoz J.R., Prósper F.. Mini review: Advances and challenges in CAR-T cell therapy: from early chimeric antigen receptors to future frontiers in oncology. Frontiers in Hematology. 2023. DOI: 10.3389/frhem.2023.1217775.

Bobadilla Muñoz M., Orbe J., Abizanda G., Machado F.J.D., Vilas A., Ullate-Agote A., Extramiana L., Baraibar Churio A., Aranguren X.L., Cantero G., Sáinz Amillo N., Rodríguez J.A., Ramos García L., Romero Riojas J.P., Vallejo-Illarramendi A., Paradas C., López de Munain A., Páramo J.A., Prósper F., Pérez-Ruiz A.. Loss of the matrix metalloproteinase-10 causes premature features of aging in satellite cells. Frontiers in Cell and Developmental Biology. 2023. DOI: 10.3389/fcell.2023.1128534.

Sadeghlar F., Seelemann J., Vogt A., Möhring C., Zhou T., Mahn R., Kornek M., Lukacs-Kornek V., Casares N., Lasarte J.J., Sarobe P., van Beekum C., Matthaei H., Manekeller S., Kalff J., Schmidt-Wolf I.G.H., Strassburg C.P., Gonzalez-Carmona M.A.. Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma. Immunological Investigations. 2023. DOI: 10.1080/08820139.2023.2261980.

Calviño C., Ceballos C., Alfonso A., Jauregui P., Calleja-Cervantes M.E., San Martin-Uriz P., Rodriguez-Marquez P., Martin-Mallo A., Iglesias E., Abizanda G., Rodriguez-Diaz S., Martinez-Turrillas R., Illarramendi J., Viguria M.C., Redondo M., Rifon J., Villar S., Lasarte J.J., Inoges S., Lopez-Diaz de Cerio A., Hernaez M., Prosper F., Rodriguez-Madoz J.R.. Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia. Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1270843.

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