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Gómez-Aguililla S., Farrais S., Senosiain C., López-Palacios N., Arau B., Ruiz-Carnicer Á., Sánchez-Domínguez R., Corzo M., Casado I., Pujals M., Bodas A., Sousa C., Núñez C.. Elucidating Immune Cell Changes in Celiac Disease: Revealing New Insights from Spectral Flow Cytometry. International Journal of Molecular Sciences. April 2025. DOI: 10.3390/ijms26072877.

Diez B., Calviño C., Fernández-García M., Rodríguez-Márquez P., Rodríguez-Díaz S., Martínez-Turillas R., Ceballos C., Illarramendi J., Serrano-López J., Miskey C., Navarro-Bailón A., López-Corral L., Llamas P., Redondo M., Sánchez-Guijo F., Rifon J., Alfonso-Piérola A., Ivics Z., Inogés S., López-Díaz de Cerio A., Yanez R., Bueren J.A., Rodríguez-Madoz J.R., Prosper F.. Generation and GMP scale-up of human CAR-T cells using non-viral Sleeping Beauty transposons for B cell malignances. Molecular Therapy Methods and Clinical Development. 13 March 2025. DOI: 10.1016/j.omtm.2025.101425.

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Valencia J., Yáñez R.M., Muntión S., Fernández-García M., Martín-Rufino J.D., Zapata A.G., Bueren J.A., Vicente Á., Sánchez-Guijo F.. Improving the therapeutic profile of MSCs: Cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity. Frontiers in Immunology. 2025. DOI: 10.3389/fimmu.2025.1473788.

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Garcia Gómez-Heras S., Garcia-Arranz M., Vega-Clemente L., Olivera-Salazar R., Vélez Pinto J.F., Fernández-García M., Guadalajara H., Yáñez R., Garcia-Olmo D.. Study of the Effect of Wild-Type and Transiently Expressing CXCR4 and IL-10 Mesenchymal Stromal Cells in a Mouse Model of Peritonitis. International Journal of Molecular Sciences. January 2024. DOI: 10.3390/ijms25010520.

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Medina J.P., Bermejo-Álvarez I., Pérez-Baos S., Yáñez R., Fernández-García M., García-Olmo D., Mediero A., Herrero-Beaumont G., Largo R.. Corrigendum: MSC therapy ameliorates experimental gouty arthritis hinting an early COX-2 induction (Front. Immunol., (2023), 14, 1193179, 10.3389/fimmu.2023.1193179). Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1345777.

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Serrano L.J., Garcia‐arranz M., De Pablo‐Moreno J.A., Segovia J.C., Olivera‐salazar R., Garcia‐olmo D., Liras A.. Development and Characterization of a Factor V‐Deficient CRISPR Cell Model for the Correction of Mutations. International Journal of Molecular Sciences. May-2 2022. DOI: 10.3390/ijms23105802.

López-Valls M., Escalona-Noguero C., Rodríguez-Díaz C., Pardo D., Castellanos M., Milán-Rois P., Martínez-Garay C., Coloma R., Abreu M., Cantón R., Galán J.C., Miranda R., Somoza Á., Sot B.. CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles. Analytica Chimica Acta. 1 May 2022. DOI: 10.1016/j.aca.2022.339749.

Torra J., Viela F., Megías D., Sot B., Flors C.. Versatile Near-Infrared Super-Resolution Imaging of Amyloid Fibrils with the Fluorogenic Probe CRANAD-2. Chemistry - A European Journal. 1 April 2022. DOI: 10.1002/chem.202200026.

Quintana-Bustamante O., Fañanas-Baquero S., Dessy-Rodriguez M., Ojeda-Pérez I., Segovia J.C.. Gene Editing for Inherited Red Blood Cell Diseases. Frontiers in Physiology. 28 March 2022. DOI: 10.3389/fphys.2022.848261.

Schwartz J.D., Barcellini W., Grace R.F., Bianchi P., Zanella A., López Lorenzo J.L., Sevilla J., Shah A.J., Glader B., Nicoletti E., Navarro Ordoñez S., Segovia J.C.. Who should be eligible for gene therapy clinical trials in red blood cell pyruvate kinase deficiency (PKD)?: Toward an expanded definition of severe PKD. American Journal of Hematology. 1 March 2022. DOI: 10.1002/ajh.26458.

López-Muneta L., Linares J., Casis O., Martínez-Ibáñez L., González Miqueo A., Bezunartea J., Sanchez de la Nava A.M., Gallego M., Fernández-Santos M.E., Rodriguez-Madoz J.R., Aranguren X.L., Fernández-Avilés F., Segovia J.C., Prósper F., Carvajal-Vergara X.. Generation of NKX2.5^GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts. Frontiers in Cell and Developmental Biology. 21 January 2022. DOI: 10.3389/fcell.2021.797927.

Rubio C., Avendaño-Ortiz J., Ruiz-Palomares R., Karaivanova V., Alberquilla O., Sánchez-Domínguez R., Casalvilla-Dueñas J.C., Montalbán-Hernández K., Lodewijk I., Rodríguez-Izquierdo M., Munera-Maravilla E., Nunes S.P., Suárez-Cabrera C., Pérez-Crespo M., Martínez V.G., Morales L., Pérez-Escavy M., Alonso-Sánchez M., Lozano-Rodríguez R., Cueto F.J., Aguirre L.A., Guerrero-Ramos F., Paramio J.M., López-Collazo E., Dueñas M.. Toward Tumor Fight and Tumor Microenvironment Remodeling: PBA Induces Cell Cycle Arrest and Reduces Tumor Hybrid Cells’ Pluripotency in Bladder Cancer. Cancers. January-2 2022. DOI: 10.3390/cancers14020287.

Malouf C., Loughran S.J., Wilkinson A.C., Shimamura A., Río P.. Translational research for bone marrow failure patients. Experimental Hematology. January 2022. DOI: 10.1016/j.exphem.2021.11.004.

Solanes-Casado S., Cebrián A., Rodríguez-Remírez M., Mahíllo I., García-García L., Río-Vilariño A., Baños N., de Cárcer G., Monfort-Vengut A., Castellano V., Fernández-Aceñero M.J., García-Foncillas J., del Puerto-Nevado L.. Overcoming PLK1 inhibitor resistance by targeting mevalonate pathway to impair AXL-TWIST axis in colorectal cancer. Biomedicine and Pharmacotherapy. December 2021. DOI: 10.1016/j.biopha.2021.112347.

Carrascoso-Rubio C., Zittersteijn H.A., Pintado-Berninches L., Fernández-Varas B., Lozano M.L., Manguan-Garcia C., Sastre L., Bueren J.A., Perona R., Guenechea G.. Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1. Stem Cell Research and Therapy. December 2021. DOI: 10.1186/s13287-021-02145-8.

Soria-Juan B., Garcia-Arranz M., Llanos Jiménez L., Aparicio C., Gonzalez A., Mahillo Fernandez I., Riera del Moral L., Grochowicz L., Andreu E.J., Marin P., Castellanos G., Moraleda J.M., García-Hernández A.M., Lozano F.S., Sanchez-Guijo F., Villarón E.M., Parra M.L., Yañez R.M., de la Cuesta Diaz A., Tejedo J.R., Bedoya F.J., Martin F., Miralles M., del Rio Sola L., Fernández-Santos M.E., Ligero J.M., Morant F., Hernández-Blasco L., Andreu E., Hmadcha A., Garcia-Olmo D., Soria B.. Efficacy and safety of intramuscular administration of allogeneic adipose tissue derived and expanded mesenchymal stromal cells in diabetic patients with critical limb ischemia with no possibility of revascularization: study protocol for a randomized controlled double-blind phase II clinical trial (The NOMA Trial). Trials. December 2021. DOI: 10.1186/s13063-021-05430-2.

Hervás-Salcedo R., Fernández-García M., Hernando-Rodríguez M., Quintana-Bustamante O., Segovia J.C., Alvarez-Silva M., García-Arranz M., Minguez P., del Pozo V., de Alba M.R., García-Olmo D., Ayuso C., Lamana M.L., Bueren J.A., Yañez R.M.. Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10. Stem Cell Research and Therapy. December 2021. DOI: 10.1186/s13287-021-02193-0.

Lozano-Pedraza C., Plaza-Mayoral E., Espinosa A., Sot B., Serrano A., Salas G., Blanco-Andujar C., Cotin G., Felder-Flesch D., Begin-Colin S., Teran F.J.. Assessing the parameters modulating optical losses of iron oxide nanoparticles under near infrared irradiation. Nanoscale Advances. 21 November 2021. DOI: 10.1039/d1na00601k.

Lopez-Santalla M., Garin M.I.. Improving the efficacy of mesenchymal stem/stromal-based therapy for treatment of inflammatory bowel diseases. Biomedicines. November 2021. DOI: 10.3390/biomedicines9111507.

García-García L., Fernández-Tabanera E., Cervera S.T., de Mera R.M.M.F., Josa S., González-González L., Rodríguez-Martín C., Grünewald T.G.P., Alonso J.. The transcription factor fezf1, a direct target of ewsr1-fli1 in ewing sarcoma cells, regulates the expression of neural-specific genes. Cancers. November-2 2021. DOI: 10.3390/cancers13225668.

Büning H., Wilson E., Bueren J., Schambach A., Auricchio A.. The European Society of Gene and Cell Therapy: A Nearly 30-Year Endeavor to Make Gene Therapy a Clinical Reality. Human Gene Therapy. October 2021. DOI: 10.1089/hum.2021.29183.hbu.

Navarro S., Quintana-Bustamante O., Sanchez-Dominguez R., Lopez-Manzaneda S., Ojeda-Perez I., Garcia-Torralba A., Alberquilla O., Law K., Beard B.C., Bastone A., Rothe M., Villanueva M., Ramirez J.C., Fañanas-Baquero S., Nieto-Romero V., Molinos-Vicente A., Gutierrez S., Nicoletti E., García-Bravo M., Bueren J.A., Schwartz J.D., Segovia J.C.. Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment. Molecular Therapy Methods and Clinical Development. 10 September 2021. DOI: 10.1016/j.omtm.2021.07.006.

Sevilla J., Navarro S., Rio P., Sánchez-Domínguez R., Zubicaray J., Gálvez E., Merino E., Sebastián E., Azqueta C., Casado J.A., Segovia J.C., Alberquilla O., Bogliolo M., Román-Rodríguez F.J., Giménez Y., Larcher L., Salgado R., Pujol R.M., Hladun R., Castillo A., Soulier J., Querol S., Fernández J., Schwartz J., García de Andoín N., López R., Catalá A., Surralles J., Díaz-de-Heredia C., Bueren J.A.. Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes. Molecular Therapy Methods and Clinical Development. 10 September 2021. DOI: 10.1016/j.omtm.2021.06.001.

Fañanas-Baquero S., Quintana-Bustamante O., Dever D.P., Alberquilla O., Sanchez-Dominguez R., Camarena J., Ojeda-Perez I., Dessy-Rodriguez M., Turk R., Schubert M.S., Lattanzi A., Xu L., Lopez-Lorenzo J.L., Bianchi P., Bueren J.A., Behlke M.A., Porteus M., Segovia J.C.. Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency. Molecular Therapy Methods and Clinical Development. 10 September 2021. DOI: 10.1016/j.omtm.2021.05.001.

Cervera S.T., Rodríguez-Martín C., Fernández-Tabanera E., Melero-Fernández de Mera R.M., Morin M., Fernández-Peñalver S., Iranzo-Martínez M., Amhih-Cardenas J., García-García L., González-González L., Moreno-Pelayo M.A., Alonso J.. Therapeutic potential of ewsr1–fli1 inactivation by crispr/cas9 in ewing sarcoma. Cancers. 1 August 2021. DOI: 10.3390/cancers13153783.

Ramírez M.J., Pujol R., Trujillo-Quintero J.P., Minguillón J., Bogliolo M., Río P., Navarro S., Casado J.A., Badell I., Carrasco E., Balmaña J., Català A., Sevilla J., Beléndez C., Argilés B., López M., Díaz de Heredia C., Rao G., Nicoletti E., Schwartz J.D., Bueren J.A., Surrallés J.. Natural gene therapy by reverse mosaicism leads to improved hematology in Fanconi anemia patients. American Journal of Hematology. 1 August 2021. DOI: 10.1002/ajh.26234.

Leivas A., Valeri A., Córdoba L., García-Ortiz A., Ortiz A., Sánchez-Vega L., Graña-Castro O., Fernández L., Carreño-Tarragona G., Pérez M., Megías D., Paciello M.L., Sánchez-Pina J., Pérez-Martínez A., Lee D.A., Powell D.J., Río P., Martínez-López J.. NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma. Blood Cancer Journal. August 2021. DOI: 10.1038/s41408-021-00537-w.

Leceta J., Garin M.I., Conde C.. Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis. Frontiers in Immunology. 16 July 2021. DOI: 10.3389/fimmu.2021.701862.

Lopez-Santalla M., Bueren J.A., Garin M.I.. Mesenchymal stem/stromal cell-based therapy for the treatment of rheumatoid arthritis: An update on preclinical studies. EBioMedicine. July 2021. DOI: 10.1016/j.ebiom.2021.103427.

Fernandez-Perez R., Lopez-Santalla M., Sánchez-Domínguez R., Alberquilla O., Gutiérrez-Cañas I., Juarranz Y., Bueren J.A., Garin M.I.. Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis. Frontiers in Immunology. 28 June 2021. DOI: 10.3389/fimmu.2021.687443.

Bonafont J., Mencía A., Chacón-Solano E., Srifa W., Vaidyanathan S., Romano R., Garcia M., Hervás-Salcedo R., Ugalde L., Duarte B., Porteus M.H., Del Rio M., Larcher F., Murillas R.. Correction of recessive dystrophic epidermolysis bullosa by homology-directed repair-mediated genome editing. Molecular Therapy. 2 June 2021. DOI: 10.1016/j.ymthe.2021.02.019.

Fañanas-Baquero S., Orman I., Aparicio F.B., de Miguel S.B., Merino J.G., Yañez R., Sainz Y.F., Sánchez R., Dessy-Rodríguez M., Alberquilla O., Alfaro D., Zapata A., Bueren J.A., Segovia J.C., Quintana-Bustamante O.. Natural estrogens enhance the engraftment of human hematopoietic stem and progenitor cells in immunodeficient mice. Haematologica. June 2021. DOI: 10.3324/haematol.2019.233924.

Gálvez E., Vallespín E., Arias-Salgado E.G., Sánchez-Valdepeñas C., Giménez Y., Navarro S., Río P., Bogliolo M., Pujol R., Peiró M., Nevado J., Zubicaray J., Sebastián E., Catalá A., Beléndez C., Díaz De Heredia C., Galera A., Badell I., Madero L., Perona R., Sastre L., Surrallés J., Bueren J., Lapunzina P., Sevilla J.. Next-generation Sequencing in Bone Marrow Failure Syndromes and Isolated Cytopenias: Experience of the Spanish Network on Bone Marrow Failure Syndromes. HemaSphere. 9 April 2021. DOI: 10.1097/HS9.0000000000000539.

Errazquin R., Sieiro E., Moreno P., Ramirez M.J., Lorz C., Peral J., Ortiz J., Casado J.A., Roman-Rodriguez F.J., Hanenberg H., Río P., Surralles J., Segrelles C., Garcia-Escudero R.. Generating new fanca-deficient hnscc cell lines by genomic editing recapitulates the cellular phenotypes of fanconi anemia. Genes. April 2021. DOI: 10.3390/genes12040548.

Escalona-Noguero C., López-Valls M., Sot B.. CRISPR/Cas technology as a promising weapon to combat viral infections. BioEssays. April 2021. DOI: 10.1002/bies.202000315.

García-Bernal D., García-Arranz M., Yáñez R.M., Hervás-Salcedo R., Cortés A., Fernández-García M., Hernando-Rodríguez M., Quintana-Bustamante Ó., Bueren J.A., García-Olmo D., Moraleda J.M., Segovia J.C., Zapata A.G.. The Current Status of Mesenchymal Stromal Cells: Controversies, Unresolved Issues and Some Promising Solutions to Improve Their Therapeutic Efficacy. Frontiers in Cell and Developmental Biology. 16 March 2021. DOI: 10.3389/fcell.2021.650664.

Pintado-Berninches L., Montes-Worboys A., Manguan-García C., Arias-Salgado E.G., Serrano A., Fernandez-Varas B., Guerrero-López R., Iarriccio L., Planas L., Guenechea G., Egusquiaguirre S.P., Hernandez R.M., Igartua M., Luis Pedraz J., Cortijo J., Sastre L., Molina-Molina M., Perona R.. GSE4-loaded nanoparticles a potential therapy for lung fibrosis that enhances pneumocyte growth, reduces apoptosis and DNA damage. FASEB Journal. March 2021. DOI: 10.1096/fj.202001160RR.

ElMaghloob Y., Sot B., McIlwraith M.J., Garcia E., Yelland T., Ismail S., Pfeffer S.R.. ARL3 activation requires the co-GEF BART and effector-mediated turnover. eLife. January 2021. DOI: 10.7554/eLife.64624.

López-Manzaneda S., Ojeda-Pérez I., Zabaleta N., García-Torralba A., Alberquilla O., Torres R., Sánchez-Domínguez R., Torella L., Olivier E., Mountford J., Ramírez J.C., Bueren J.A., González-Aseguinolaza G., Segovia J.C.. In Vitro and In Vivo Genetic Disease Modeling via NHEJ-Precise Deletions Using CRISPR-Cas9. Molecular Therapy Methods and Clinical Development. 11 December 2020. DOI: 10.1016/j.omtm.2020.10.007.

Rodríguez-Remírez M., Del Puerto-Nevado L., Fernández-Aceñero M.J., Cruz-Ramos M., García-García L., Solanes S., Molina-Roldán E., García-Foncillas J., Cebrián A.. Targeting Galectin-1 by Aflibercept Strongly Enhances Its Antitumor Effect in Neuroendocrine Carcinomas. Neuroendocrinology. December 2020. DOI: 10.1159/000506163.

Pino-Barrio M.J., Giménez Y., Villanueva M., Hildenbeutel M., Sánchez-Dominguez R., Rodríguez-Perales S., Pujol R., Surrallés J., Río P., Cathomen T., Mussolino C., Bueren J.A., Navarro S.. TALEN mediated gene editing in a mouse model of Fanconi anemia. Scientific Reports. 1 December 2020. DOI: 10.1038/s41598-020-63971-z.

Martinez-Lage M., Torres-Ruiz R., Puig-Serra P., Moreno-Gaona P., Martin M.C., Moya F.J., Quintana-Bustamante O., Garcia-Silva S., Carcaboso A.M., Petazzi P., Bueno C., Mora J., Peinado H., Segovia J.C., Menendez P., Rodriguez-Perales S.. In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells. Nature Communications. 1 December 2020. DOI: 10.1038/s41467-020-18875-x.

Vázquez A., Fernández-Sevilla L.M., Jiménez E., Pérez-Cabrera D., Yañez R., Subiza J.L., Varas A., Valencia J., Vicente A.. Involvement of Mesenchymal Stem Cells in Oral Mucosal Bacterial Immunotherapy. Frontiers in Immunology. 19 November 2020. DOI: 10.3389/fimmu.2020.567391.

Lopez-Santalla M., Hervas-Salcedo R., Fernandez-Garcia M., Bueren J.A., Garin M.I.. Cell Therapy with Mesenchymal Stem Cells Induces an Innate Immune Memory Response That Attenuates Experimental Colitis in the Long Term. Journal of Crohn's and Colitis. 1 October 2020. DOI: 10.1093/ecco-jcc/jjaa079.

Luengo Y., Sot B., Salas G.. Combining Ag and γ-Fe<inf>2</inf>O<inf>3</inf> properties to produce effective antibacterial nanocomposites. Colloids and Surfaces B: Biointerfaces. October 2020. DOI: 10.1016/j.colsurfb.2020.111178.

Rodriguez-Fornes F., Quintana-Bustamante O., Lozano M.L., Segovia J.C., Bueren J.A., Guenechea G.. Targeted gene therapy into a safe harbor site in human hematopoietic progenitor cells. Gene Therapy. 1 September 2020. DOI: 10.1038/s41434-020-0144-x.

Lopez-Santalla M., Fernandez-Perez R., Garin M.I.. Mesenchymal stem/stromal cells for rheumatoid arthritis treatment: An update on clinical applications. Cells. August 2020. DOI: 10.3390/cells9081852.

Torra J., Bondia P., Gutierrez-Erlandsson S., Sot B., Flors C.. Long-term STED imaging of amyloid fibers with exchangeable Thioflavin T. Nanoscale. 28 July 2020. DOI: 10.1039/d0nr02961k.

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